COLCHICUM.
CONDITIONS.
► Aggravation.
► (Morning),
Confusion in the head; after rising, especially on shaking head, feeling in head; on waking,
pain in right forehead; tongue coated; rawness in
throat, etc.; on waking, nausea, etc., pain in stomach; on waking, pressure in upper
abdomen; diarrhœa-like stool; in bed, burning in urethra; in bed, stitches in left chest;
on waking, palpitation; on waking, drawing in small of back; bruised feeling in small of
back; weakness of limbs; limbs feel weary; drawing in muscles of shoulders, eyes; weakness;
on waking, weariness; on rising, weariness. ► (Forenoon), Eructations. ► (Afternoon), Frontal headache; towards evening, headache from
forehead towards occiput; hunger; thirst; urging to stool; slimy stool; pressure in præcordial
region; palpitation; pressure in sacrum, especially immediately after dinner; sensation in
whole body; sleepiness; chilliness; after dinner,
coldness; cold feet; flushes of heat. ► (Evening), Headache; headache
in temple; pressure in temple; epistaxis; great appetite; while walking, pain in stomach;
stitches in spleen; pain in abdomen; after eating, feeling in chest; in bed, drawing in
thigh; in bed, tearing in middle of thigh; in bed, knee-joint painful; in bed, pain above
knee; pain in whole body; griping, etc.; in toes; pains become intolerable; sensation of
coldness. ► (Night),
From beginning of night to break of day, all the varieties of pain; delirium; great flow of
thoughts; colic, etc.; about 10 o’clock, pains in left chest; while lying on left side,
fulness, etc., in heart; audible palpitation; pain in sacrum; uneasiness in all limbs; on
moving about, pain in hip-bone; tearing in region of hip; towards morning, lascivious
dreams; chilliness, etc.; heat of body; dry heat; sweat.
► (After midnight),
After waking, slight sweat. ► (Open
air), Lachrymation. ► (Bending forward), Heaviness in occiput. ►
(Bending head backward), Headache in occiput. ► (On blowing nose), Pain
in left chest. ► (Coffee),
Aggravation. ► (During dinner),
Nausea. ► (After dinner),
Nausea; irritation in lower abdomen; pasty stool; yawning, etc. ►
(After eating), Headache above eye; nausea; fulness in
abdomen; sexual desire. ► (Erect
position), Nausea; crawling in stomach. ► (Lying quiet), Backache. ► (Mental exertion), Symptoms very greatly aggravated. ► (Motion), Heaviness in
occiput; pain over eye; vomiting; drawing in small of back; especially on flexion of hand,
pain in metacarpus. ► (Pressure),
Pain in region of spleen; sensation in upper abdomen. ► (Raising eyes), Headache in occiput. ►
(On rising), Vertigo. ►
(Rising up in bed), The symptoms. ►
(On going into room after walking in open air), Pain in
head. ► (While sitting),
Sensation of warmth, etc. ► (Sitting
a long time), Pain in scapula. ► (Sitting still), Throbbing in cervical arteries. ► (While sitting after walking),
Vertigo. ► (On going to sleep),
Palpitation of heart. ► (Standing),
Nausea, etc.; pain at union of last vertebræ with sacrum. ►
(On going up steps), Knee feels broken. ► (After stool), Faintness;
weariness, etc. ► (Walking),
Fulness, etc., in epigastric region; oppression of chest; pain at union of last vertebræ
with sacrum. ► (During long walk),
Sensation in bend of knee. ► (Walking
in wind), Confusion of forehead. ► (Work), Especially reading or writing, very much affected. ► Amelioration. ► (Night), Sensation in upper arm. ►
(Open air), General relief; headache above eyes. ► (Cold), Pain in frontal
eminence. ► (Eructation),
Sensation in abdomen; colic. ► (Motion),
Backache; especially in open air, sensation in whole body. ►
(Pressure), Pain in frontal eminence. ► (Rest), Sensation in
upper abdomen. ► (Rest in bed),
Pain in forehead; headache in temple; chilliness. ► (In room), Confusion of forehead. ►
(Rubbing with hand), Sensation in abdomen. ► (Sleep), Headache. ► (Vomiting), Nausea. ► (Walking around),
Pressure, etc., in præcordial region. ► (Warmth), Pain in forehead.
SUPPLEMENT: COLCHICUM.
Authorities.
86, J. Y.
Clark, M.D., Am. Med. Rec., vol. i, 1818, p. 369, John R. Peckworth took 100 drops of
tincture; 87, ibid., the author took 100 drops; 88, Thos. Kennard, M.D., Am. J. of M. S., 1857 (1), p. 69, a
woman, æt. fifty-six years, took one ounce of Colch. wine in twelve hours; 89, Dr. Fifield, Bost. Med. and Surg. Journ., vol. lvi, 1857, p.
78, a man, æt. twenty-eight years, suffering from rheumatism, took half an ounce of Colch.
wine; 90, W. A. Hammond, M.D., Am. Med. Monthly, Feb.,
1861, p. 83, took 1 fluid drachm at 8 A.M., 2 and 10 P.M. (first day); 1 1/2 fluid drachms
three times (second and third days); 1/2 drachm (fourth day); 1 1/2 drachms (fifth day); 91, ibid., a man, æt. twenty-three years, took 1 drachm tincture
three times (first day); 1 1/2 drachms three times (second day); 92,
John H. Garner, M.D., Canada Lancet, vol. iii, 1871, p. 307, R. H. drank about a pint of
tincture; 93, ibid., J. M. J. took same quantity; 94, ibid. T. H. took a small quantity; 95,
W. E. Porter, Med. Times and Gaz., 1874 (2), 723, poisoning of two children, æt. four and
two years; 96, Canada Pharm. Journ. (Pacif. M. and S.
Journ., April, 1874, p. 572), a party of seventeen persons drank from one or two ounces to a
pint each, of the wine, seven died; 97, J. Pierre,
Comptes Rendus, vol. lxxix, p. 633 (Pharm. Journ. and Trans., Oct., 1864, p. 325), the
author plucked some fully expanded flowers, afterwards extended his hand over a large clump
of flowers, carefully avoiding all contact, with the same result.
MIND.
► Muttered and raved
wildly at times, but it only lasted a few minutes, [93].
► Comatose, [92].
HEAD.
[1190.] ► Intense headache, [92].
EYE.
► Eyes red and watery,
and the pupils dilated, [92].
EAR.
FACE.
► Expression of
countenance anxious and haggard, [92]. ► Hectic flush occasionally on cheek-bones, [92].
MOUTH.
► Tongue dry and
brown in the centre, and red along the edges, [92].
STOMACH.
► Great thirst, [92], [95]. ► Nausea, [94]. ► Sickness, [95]. ► Vomiting in from three-fourths of an hour to an hour and a
half, [96]. [1200.]
► The ejecta were bilious, and then of the rice-water
character, [96].
ABDOMEN.
► Extreme
tenderness over abdomen, and the intermittent severe pains precisely similar to peritonitis,
[92]. ► Tormina, [95].
RECTUM AND ANUS.
STOOL.
► Purging, [96]. ► Severe diarrhœa
(second day), [91]. ►
Purged and vomited violently, [92]. ► Purging in from three-fourths of an hour to an hour and a
half, when a large quantity was taken; later when the quantity was small, [96].
URINARY ORGANS.
► In three
days immediately preceding commencement of experiment, the average quantity of urine for
each day was 1425 cubic cent. of sp. gr. 1021.73. The average amount of solid matter was
64.28 grams; of which 30.18 were inorganic, and 34.10 organic substance. The average amount
of uric acid excreted for each period of twenty-four hours was 0.77 grams. Quantity of urine
excreted 1685 cubic cent., sp. gr. 1021.5; total amount of solids 70.15 grams, of which
30.90 were inorganic, and 39.25 organic matter; quantity of uric acid 0.81 gram (first day).
Quantity of urine 1720 cc., sp. gr. 1020.87; total solids 75.29 grams; inorganic solids
32.44 grams; organic solids 42.85 grams; uric acid 0.69 grams (second day). Quantity of
urine 1784 cc.; sp. gr. 1022.57; total solids 80.13 grams; inorganic salts 35.11 grams;
organic solids 45.03 grams; uric acid 0.82 gram (third day). Quantity of urine 1540 c.c.;
sp. gr. 1023.17; total solids 69.23 grams; inorganic solids 31.09; organic solids 38.14;
uric acid 0.78 gram (fourth day). Quantity of urine 1698 cc.; sp. gr. 1023.68; total solids
76.14 grams; inorganic solids 32.36 grams; organic solids 42.88 grams; uric acid 0.76 gram
(fifth day), [90]. ►
Average daily quantity of urine 989 cc.; sp. gr. 1020.14; total solids 51.20 grams;
inorganic solids 22.45 grams; organic solids 28.75 grams; uric acid 0.47 gram (before
experiment); quantity of urine 1021 cc.; sp. gr. 1024.18; total solids 63.25 grams.
inorganic solids 23.57 grams; organic solids 40.68 grams; uric acid 0.59 gram (first day);
quantity of urine 8875 cc.; sp. gr. 1026.11; total solids 60.25 grams; inorganic solids
20.38 grams; organic solids 39.87 grams; uric acid 0.51 gram (second day), [91].
RESPIRATORY ORGANS.
[1210.]
► Coughed severely at regular intervals, [92]. ► Blood in sputa, [92]. ► Breathing rapid;
heavy, almost stertorous (after a few hours), [92].
CHEST.
► Great fulness of
the chest, [92].
PULSE.
► Pulse 80 (before
experiment); 78 (in five and ten minutes); 76 (in fifteen and twenty minutes); 78 (in
twenty-five and thirty minutes); 80 (in thirty-five, forty, and forty-five minutes); 78 (in
fifty minutes); 76 (in fifty-five minutes); 72 (in sixty minutes); 70 (in sixty-five
minutes); 68 (in seventy and seventy-five minutes); 72 (in eighty and ninety-five minutes);
70 (in one hundred minutes); 72 (in one hundred and five, one hundred and ten, and one
hundred and fifteen minutes); 76 (in one hundred and twenty minutes); 80 (in one hundred and
eighty and two hundred and forty minutes), [86]. ► In five minutes after taking the medicine, his pulse became
considerably reduced, both in force and frequency; in thirty-five minutes he had a copious
discharge of pale-colored urine, his pulse much increased; in fifty minutes, very sleepy,
pulse again reduced; in seventy minutes, his mental faculties became much exhilarated, pulse
very slow and soft; in ninety minutes, perfectly free from any peculiar feelings, pulse
somewhat increased; in one hundred and eighty minutes, pulse very natural, [86]. ► Pulse 70 (before
experiment); 52 (in five minutes); 48 (in ten minutes); 46 (in fifteen minutes); 42 (in
twenty and twenty-five minutes); 48 (in thirty minutes); 43 (in thirty-five minutes); 45 (in
forty and forty-five minutes); 39 (in fifty minutes); 43 (in fifty-five minutes); 46 (in
sixty minutes); 50 (in sixty-five, seventy, and seventy-five minutes); 45 (in eighty,
eighty-five, and ninety minutes); 47 (in ninety-five minutes); 50 (in one hundred, one
hundred and five, one hundred and ten, one hundred and fifteen, one hundred and twenty, and
one hundred and twenty-five minutes); 53 (in one hundred and thirty minutes); 55 (in one
hundred and thirty-five minutes); 57 (in one hundred and forty minutes); 60 (in one hundred
and forty-five, one hundred and fifty, one hundred and fifty-five, one hundred and sixty,
and one hundred and sixty-five minutes); 65 (in two hundred minutes); 70 (in two hundred and
seventy-five and three hundred minutes), [87]. ► In five minutes after taking the medicine my pulse became
diminished, both in force and frequency; in fifteen minutes I felt considerable flushes of
heat passing over my face, and followed by a considerable degree of vertigo; in fifty
minutes, my pulse became still more diminished; in sixty-five minutes, I was somewhat
sleepy; and in seventy-five minutes, I was very sleepy, attended with a slight diaphoresis;
in one hundred and thirty minutes, my pulse began to increase in frequency, but continued
diminished in force; and in two hundred and thirty-five minutes, was natural, both as to
force and frequency, [57]. ►
Pulse 160; grew feeble (after a few hours), [92].
SUPERIOR EXTREMITIES.
►
Numbness in the arms, [97]. [1220.]
► In a few seconds his fingers changed color, and took
the livid greenish tint characteristic of a corpse in a state of incipient decomposition.
After about ten seconds the skin regained its color, [97].
► Cramps of the fingers, [96].
GENERALITIES.
►
Convulsions, [95]. ►
Extreme prostration, suffering from excessive nausea and vomiting, with slight purging, heat
and burning in the fauces, inordinate thirst, cold, clammy skin, feeble pulse, violent supra
orbital pain, and distressing gastralgia, with very anxious countenance, [88]. ► Pale, cold, vomiting
constantly, purging, and complaining of great thirst and pain at the epigastrium, [89]. ► The symptoms were
mainly those of violent cholera morbus, [96]. ► Debility, [94]. ► Very much exhausted, [92].
► Similar symptoms, but milder, except the headache,
which he described as most intense, [93].
SLEEP.
FEVER.
[1230.] ► Shivering, [95]. ► Coldness, [95]. ► Whole body clammy and cold, [92].
► Feet and hands cold, [92].
► Cold sweat on forehead, [92].® 2000
Article