KALI IODATUM.
FEVER.
►
Chilliness. ► Chilliness
from afternoon till the next morning (after forty-six days), [1]. ►
Chilliness from 6 to 10 P.M., disappearing after lying down (after five
days), [1]. [780.] ►
Chilliness with sleepiness, from 6 to 8 P.M., beginning by creeping up
the back, and extending over the whole body (after seventeen days), [1]. ►
Chilliness, with shaking, at 10 P.M., lasting half an hour (third day), [1]. ►
Chilliness from 4 to 7 P.M., with thirst; she was able to get warm in
bed, but not by the stove (after fourteen days), [1]. ►
Chilliness, which was difficult to relieve by the warmth of a stove, in
the afternoon (tenth day), [1]. ► She was so chilly at night that she could
not get warm (after three days), [1].
► Shaking chill at night, on frequent
waking (after eleven days), [1]. ► Shivering (first day), [35]. ►
Shivering and coldness all over; he feels frozen, and cannot get warm
with any amount of covering, [2]. ► Violent shivering fit (one hour after
fourth dose), [9]. ► Constant shivering-creeping, with icy
coldness over the hands, with pressure and griping in the lower abdomen,
during the menses, [1]. [790.] ►
Creeping in the back, followed by coldness of the whole body, in the
evening (fourth day), [1]. ► Coldness of the feet, with swelling, [2]. ►
Heat. ► Heat of the skin
(after fourth dose), [9]. ► Heat, followed by perspiration, in the
afternoon, from 1 to 3 (third day), [1].
► Heat, with copious sweat, malaise,
itching, and bruised sensation in the skin, [2]. ► Great
heat, as after overexertion, followed by excessive coldness with
trembling, [2]. ► Flushes of heat, with dulness in the head
and discomfort of the body (fourth day), [1].
► Symptoms of fever (after some
days), [17]. ►
Fever, especially in the morning on waking, in the evening when going to
bed, and during the night, [2]. ► Fever, with languor, coldness of the back
and legs, urgent thirst, longing for sugared water, and loss of
appetite, [2]. [800.] ► Slight attack of fever, [17a]. ► Smart
fever with the nausea and vomiting (fourth day), [34]. ► Heat
of head (three hours after third dose), [26].
► The head felt hot, while the rest
of the body shivered, in the morning, [24].
► Great heat in the head, with
burning and redness of the face, [1].
► Sweat. ►
Profuse sweat, especially in the morning in bed, [2]. ► Skin
covered with perspiration, without thirst (after three hours), [25].
CONDITIONS.
►
Aggravation. ► (Morning), Vertigo at 5 o’clock, disappearing
after rising; headache; after rising, heaviness in side of forehead;
heaviness in sides of head, disappearing in open air; screwing together
in head; in bed, stitches from jaw to parietal bone; in bed, when lying
on it, tearing, etc., in zygoma; after waking, lips full of mucus; from
4 to 5 o’clock, jerking in eyetooth; after rising, odor from mouth;
after waking, numbness of mouth; in bed, rawness, etc., in throat; after
waking, distension of abdomen, etc.; after waking, pains in abdomen,
etc.; dry cough; restless sleep; on waking, fever; head hot, etc.; in
bed, sweat. ► (Forenoon), Sticking in lower jaw, etc. ► (Afternoon),
Heaviness in forehead; towards evening, heaviness in occiput; burning in
eyes; tearing in abdomen; towards evening, severe cough; sticking, etc.,
in middle of sternum; from 4 to 7 o’clock, chilliness, etc., chilliness;
from 1 to 3 o’clock, heat, etc. ► (Evening), Vertigo; headache; tearing, etc.,
in forehead; throbbing in temple; stitches in top of head; discharge of
mucus from eyes; burning in eyes; burning in lids; in bed, stitch in
ear; tearings in ear; pain over side of face; stitches, etc., in side of
throat; thirst; hiccough; pain in stomach; beating in epigastric region;
cough; dry cough, etc.; pains in chest; sticking in side of chest;
tearing in metacarpal joints; tearing in fingers; swelling of legs;
tearing in tibiæ; pain in instep; pinching in whole body; itching on
instep; from 6 to 10 o’clock, disappearing after lying down, chilliness;
from 6 to 8 o’clock, chilliness, etc.; at 10 o’clock, chilliness;
creeping in back; when going to bed, fever. ►
(Night), The symptoms; heaviness in
forehead, etc., after lying down, till midnight, jerking in eyetooth;
uneasiness in bowels; itching at anus; emission of urine; cough;
oppression, etc., of chest; pain in small of back; tearing in knees;
tearing in left knee, etc.; from afternoon till morning, chilliness;
chilly; fever. ► (Walking in open air), Grumbling in hollow
tooth. ► (Sitting
bent over), Stitches in upper left chest; pain in small of
back. ► (Cold
air), The symptoms; headache. ►
(After dinner), Heaviness of head. ► (Heat),
Headache. ► (After
meals), Vertigo; congestion of head. ►
(Motion), Pains in heart. ► (Rest),
Most symptoms. ► (Sitting), Stitches in small of back; tearings
in knee; drawing in calves; tearing in head. ►
(Standing), Tearing, etc., in calf;
tearing in heel. ► (Stooping), Stitches in forehead. ► (Talking),
Stitch in right hypochondrium, etc. ►
(Wind), Headache. ► (Walking),
Stitch in middle of chest; stitches in region of heart. ► Amelioration. ►
(Evening), After lying down, pains
in abdomen, etc. ► (Open air), Pains in abdomen. ► (Motion),
Headache; sticking in chest.
SUPPLEMENT: KALI IODATUM.
Authorities.
59,
Belgian Journal (Lancet, 1848 (2), p. 213), a man, æt. thirty-five
years, took it for five months for acne indurata on the forehead, which
it cured; 60, Prof. A. Fournier,
Med. Times and Gaz., Oct., 1877 (Amer. Journ. Med. Sci., Jan., 1878, p.
263), general effects; 61, Dr.
Colby, Pub. Mass. Hom. Med. Soc., vol. iv, 31, took one dose of 15
grains of Hydriodicum.►
He suffered from a painful sensation
of heat in his feet; in a few days this increased, and was accompanied
by a trembling of the limbs and feeling of intoxication; his movements
were uncertain from a tottering of his lower extremities; there were
vertigo, dulness of the eyes, feeble, and often double vision, with a
sensation of turning round. All these phenomena persisted for several
weeks. Shortly after, the power of moving his lips and cheeks was lost,
and he was unable to masticate. He had also vague feelings in the head,
back, and limbs, which he could not describe. A day or two afterwards
his gait was still faltering, with vertigo and feeble vision; the
countenance was that of a drunkard; speech thick and indistinct; eyes
apparently protruded, and a loss of appetite, [59]. ► In a
paper contributed to the Revue Mensuelle de
Méd. et de Chir., September, 1877, Prof. A. Fournier, of the
St. Louis Hospital, observes that while among the numerous and various
phenomena which may follow the ingestion of Iodide of potassium, there
are some which are of common occurrence and well known; there are others
which have either escaped attention, or have only been imperfectly
described. Among these may be ranged, he believes, a cutaneous
affection, consisting in the production of small miliary,
non-pruriginous, sanguinous spots, proceeding after the manner of
purpura, and to which he proposes to give the name of iodic purpura, or
petechial iodism. That the appearance of the exanthem, and the taking of
the Iodide are not a mere coincidence, he concludes from the following
observations: 1. In all cases the
purpura has appeared a very short time (from one to six days) after
commencing the Iodile. 2. In some of
the patients the same purpuric eruption has been produced several times
after each new administration of the Iodile, and in three of these it
occurred every time the medicine was used. Two cases are detailed in
which this was the case three or four times. 3.
In another case in which te purpura was produced on three successive
occasions, it was found in all these that whenever the dose was notably
increased, a marked aggravation or additional production of the eruption
ensued.As to the characteristics of this eruption, in all
the patients the well-known appearances of purpura, and the
impossibility of effacing them by pressure with the finger, were
distinctly present, the petechial color due to extravasation being very
obvious. The seat of the eruption, with one exception (when it was on
the thorax, and that only), was in all the cases on the legs only, being
always more confluent on their anterior than on their posterior part. It
never descended to the foot, or extended beyond the knee. This purpura
seems to assume an eminently discrete form, few spots being usually
observed, about a hundred of these on each limb constituting the maximum
of confluence, fifty or sixty, or even less, being the number usually
observed. On the successive appearances the purpuric spots are even yet
fewer in number. This rarity of confluence, and the especial
localization of the exanthem about the anterior tibial region, impart to
this variety of purpuric affection a somewhat peculiar physiognomy of
its own. It is always a miliary purpura, that is, a petechial eruption
of the smallest extent, resembling in size a millet-seed, the head of a
pin, or at most, and that rarely, a grain of corn, or a small lentil.
The spots are usually of a regular rounded form, and less often oval or
irregular in form, and notched. The eruption never advances beyond this
petechial and miliary condition. The spots are quite level with the
skin, seemingly incorporated with the integument, the appearance of
which they only modify by their bright color. Like as in purpura
vulgaris, these spots give rise to neither local nor constitutional
disturbance, inducing neither heat, pain, nor pruritus. Thus there is a
great chance of this eruption passing unperceived, and it is always by
accident that the patients have observed its existence, while undressing
at the bath, etc., so that many cases have no doubt escaped the notice
of patients and their attendants. The eruption comes on at an early
period of the iodic treatment, and has completed its course in two or
three days, at the end of which period it ceases to increase in
confluence, even when the use of the medicine is continued. It remains
for a certain time in the condition of purpurine petechiæ, after which
the spots undergo the ordinary changes of color observed in cutaneous
hæmorrhages, finally disappearing at the end of two or three weeks.
When under the influence of a large dose of the Iodide, a new purpuric
outbreak is produced: the intruding eruption is easily distinguished
from that which has preceded it by the bright purpurine color of its
spots, contrasting with the faded condition of the prior spots. It has a
curious appearance, this intermixture in the same locality of petechiæ
of different ages, with difference of color corresponding to the periods
of their appearance.This purpura is certainly a rare accident, or rather
phenomenon, for there are few remedies which are more employed than the
Iodide of potassium; and if iodic purpura were not almost an exceptional
occurrence, it must have attracted the attention of observers. Professor
Fournier, who, during the few years since he first became aware of its
existence, has carefully sought for it, has not met with more than some
fifteen cases.All the subjects of the affection hitherto met with
enjoyed either a flourishing or a medium condition of health; and
although some of them seemed affected with a certain degree of
“lymphatism,” none could be said to suffer from anæmia or
scrofula, and none had presented anterior hæmorrhagic proclivities. Any
of these who were the subjects of syphilis exhibited only benign or
medium forms of this, two-thirds of the cases being exempt from any
specific manifestation of this disease at the time when the Iodide, which, in fact, was administered only as a preventive,
produced the purpuric eruption. Further, in a negative point of view,
neither sex, age, occupation, nor external temperature seemed to have
exerted any influence. Nor can the eruption be attributed to excess of
dose, since most of these patients had not taken more than 15 grains of
the Iodide when the eruption had manifested itself. Still, quantity is
not a matter of indifference, for when a given dose has been followed by
purpura, a kind of tolerance of the remedy seems to be established, and
no further manifestation ensues. But let the dose be much increased,
doubled, for example, and a new outbreak of purpura may be immediately
produced, although this is less confluent and less important than that
which preceded it. But it is probably the individual
predisposition which predominates over all the etiology, for
however unknown and impenetrable in their nature, the existence of
idiosyncrasies in regard to the action of certain remedies and articles
of diet is beyond doubt. Iodic purpura in its nature takes its place in
the group of affections termed by M. Bazin, provoquées
indirectes or pathogénétiques. It is a medicinal eruption
which ranges nosologically with the roseola from Copaiba, the erythema
from Belladonna, the exanthems from Arsenic, the acne from Iodine, etc.,
[60]. ►
At night, after retiring, had a terrible spasmodic pain at the root of
the tongue, extending to both sides of the throat. For about fifteen or
twenty minutes the pain was excruciating, causing a fear that death was
impending. There was a sensation as if a spasm would close the pharynx, [61].® 2000
Article