STRYCHNINUM.
SKIN.
►
Objective. ► Skin at first
pale, became at last bluish, the face puffy and dark violet, the lips
dark blue, the neck swollen, and the jugular veins distended, [108]. ►
Skin livid, and complete redness of entire surface, [141]. ► The
skin of the body became bluish, the capillary vessels filled with venous
blood, [4]. ► Subjective. ►
Feeling of “burning all over” (after thirty minutes), [123]. ►
Sensation of burning, itching, sticking, as of large pins in the skin, [33]. [1130.]
► Prickling in the extremities, [78]. ►
Prickly sensation in the feet at intervals (forty-sixth day), [128]. ►
In the place where the drug is rubbed in there are violent burning,
sticking, and increased warmth, [29].
► Formication of the extremities, [72]. ►
Formication over the arms and lower extremities, [75]. ►
Formication of the tips of the fingers, [5].
► Intense itching of the skin of the
entire body, even of the scalp (fourteenth day), [128]. ►
Troublesome itching of the skin for about two hours (sixteenth day), [127]. ►
Itching of the skin generally, more particularly of the legs and arms
(thirty-fourth night), [128]. ► Intense itching of the skin
(thirty-seventh, forty-first, and fifty-second days), [128]. [1140.]
► Intense itching of the skin, at
night (forty-third day), [128]. ► Intense itching of the entire skin,
lasting for several hours (fifty-third day), [128]. ►
Intense itching of face, ears, and neck, at night (forty-fifth day), [128]. ►
Intense itching of face, arms, and legs (fiftieth day), [128]. ►
Itching of face, arms, and legs (forty-seventh day), [128]. ►
Violent itching of the legs (twenty-first and twenty-fourth nights), [128].
SLEEP.
►
Sleepiness. ► Yawning and
extreme weariness, in the afternoon (twenty-third day), [128]. ►
Extreme drowsiness and chilliness (second day), [128]. ►
General drowsiness, lasting for some hours (third day), [127]. ►
Sudden drowsy sensation, at 11.30 A.M. (sixth day), [128]. [1150.]
► Extreme drowsiness, with stupid
headache (fifteenth day), [128]. ► Drowsiness and loss of memory, with
extreme giddiness (seventeenth day), [128].
► Drowsiness and extreme dulness
(twenty-fifth day), [128]. ► Drowsiness, with a shattered sensation in
the head (thirty-third day), [128].
► Extreme drowsiness and yawning
(thirty-fourth day), [128]. ► Extreme drowsiness (thirty-fifth and
forty-sixth days), [128]. ► Sleeplessness. ►
Sleeplessness, with internal uneasiness, anxiety, and oppression, so
that she was unable to sleep, [24].
► Sleeplessness caused by dread of
the rectal spasms, [127]. ► Sleeplessness, visions of dead persons
(first day). ► Very sleepless night
(twenty-seventh day), [125]. [1160.] ►
Sleepless night (first and second night), [127].
► Has not slept at all during the
night, [43]. ►
Not at all drowsy, rather the opposite, [43].
► Extreme restlessness and talking in
her sleep, accompanied by a peculiar working in the back of the brain
(twentieth night), [128]. ► Restless nights, with profuse
perspiration, since the last dose, the twenty-fourth day (twenty-seventh
day), [128]. ►
Restless nights and profuse perspiration since taking the last dose, on
the thirty-first day (thirty-fourth day), [128].
► Very restless night (forty-fifth
day), [128]. ►
Rest bad (forty-seventh day), [127].
► Great restlessness (fifty-fourth
night), [128]. ► At night, disagreeable dreams; strange
wanderings of the imagination (sixth day), [128].
FEVER.
►
Chilliness. [1170.] ► Extreme chilliness (several days), [128]. ►
Extreme chilliness and drowsiness (second day), [128]. ►
Peculiar creeping chilliness all over, with a tremulous sensation in the
jaws (third day), [128]. ► Extreme chilliness, even in a warm room
(fourth day), [128]. ► Extreme chilliness and drowsiness
(twenty-fifth day), [128]. ► Slight shivering (twenty-second day), [127]. ►
Shivering, [6], [23]. ►
Shaking chill, [75]. ► Icy coldness all over, with shivering and
yawning (eleventh day), [128]. ► General coldness, especially in the
sacral region, which feels as if iced (twenty-third day), [127]. [1180.]
► Icy coldness of the entire body
(twenty-eighth day), [128]. ► A feeling of coldness suddenly came over
him; he shivered all over, and his limbs became quite rigid, [142]. ►
Whole surface of body quite cold, [139].
► Surface cold, [47], [69].
► Skin rather cool (after one hour
and a half), [45]. ► Skin cold and clammy and of a dark livid
hue, [147]. ►
Painful coldness of the head, at 3.30 P.M. (seventh day), [128]. ►
Peculiar creeping chilliness, with heat, in the right side of the head
and face (first day), [128]. ► Cold chills passing over the head and
down the back (forty-third day), [128].
► Icy coldness of the head and down
the spine (sixteenth day), [127]. [1190.] ►
A single cold chill down the entire length of the spine; afterwards she
felt deathly cold (third day), [128].
► Icy coldness down the spine,
accompanied by a kind of nervous shuddering (fourteenth day), [128]. ►
Icy coldness down the spine (fifteenth day), [128]. ► Cold
chills down the spine, at night (twenty-fifth day), [128]. ► Cold
chills down the back, frequently (twenty-first night), [128]. ► Cold
chills down the back (twenty-ninth and thirty-second days), [128]. ►
Coldness of back (fifty-second night), [128].
► Extremities cold, [88], [124],
[126], [129]. ►
Extremities cold and rigid (after six hours), [130]. ► Arms
and legs cold (after three hours and three quarters), [50]. [1200.]
► Lower extremities cold, and
perspiration flowing in a stream
from his head and chest (after twenty minutes), [42]. ► Feet
cold to touch, [43]. ► Heat. ►
Fever of an adynamic intermittent type (such as I have frequently
witnessed in Peshawar, on the northwest frontier of India), with
considerable prostration, during these seven days (thirtieth day), [127]. ►
Slight fever caused by dread of the rectal spasms, [127]. ► Began
to get hot during the spasms, [136].
► Temperature of the body higher than
usual, between the paroxysms, [57].
► Suffering from heat, [66]. ►
Temperature 100 (after seven hours), [161].
► An intolerable sense of heat
complained of over the entire body, although on same parts cool to the
feel, so that he could not bear the slightest covering, [63]. ►
Burning heat all over, with a hot sweat, [43].
[1210.] ►
Skin warm, and covered with a profuse clammy sweat, [82]. ► Body
warm, but hands and feet rather cold (after one hour), [94]. ►
Increased warmth of the body, [3].
► Sensation of warmth starting from
the abdomen and spreading over the whole body, and ending with general
profuse perspiration, [3]. ► Burning heat and great fulness in head, [43]. ►
Heat and intense pain in the head, [43].
► Sudden burning heat in the face
(twenty-seventh day), [128]. ► Sudden heat down the spine, with
trembling faint feeling, at night (seventeenth day), [128]. ► Sweat.
► Perspiration rolling off him, [121]. ►
Profuse perspiration, with restlessness (forty-fourth night), [128]. [1220.]
► Profuse perspiration, with relief
of the symptoms, [29]. ► Perspiration flowing profusely from the
face and chest (after twenty minutes), [39].
► Profuse sweat after the spasm, [49]. ►
After the attack subsided, very copious sweating ensued, [86]. ►
Profuse perspiration during sleep (forty-seventh and forty-eighth days),
[127]. ►
Skin bathed in perspiration, warm (not hot) and uniformly so, [63]. ►
Surface bathed in perspiration, [82].
► Body bathed in warm perspiration
(after seven hours), [161]. ► The skin was bedewed with perspiration,
and the capillary circulation congested, so as to give an unusual
floridness to the complexion on the upper part of the forehead,
amounting to a slight bluish or purplish color, [64]. ►
Regularly recurring perspiration, [2].
[1230.] ►
Large drops of perspiration on the face, and matting of the hair,
arising from profuse perspiration, [155].
► Perspiration of the chest became
excessively violent, [108]. ► Skin covered with cold sweat, [88], [122].
► Cold sweat, [145]. ►
Sudden cold perspiration and icy coldness of the entire body
(twenty-fourth day), [128]. ► Cold perspiration, with the convulsive
shocks and increased shaking and stiffening (forty-first day), [128].
CONDITIONS.
►
Aggravation. ► (Morning), Headache; griping pain in bowels;
weariness. ► (Evening), Thumping pain in head. ► (Night),
Toothache; symptoms. ► (Bending head down), Stiff sensation up the
spine. ► (Exertion),
Pain in back. ► (After meals), Oppression of chest. ► (Noise),
Tetanic spasms. ► (Opening mouth), Jerking sensation in stomach;
jerks in back. ► (Sitting on hard seat), Uneasiness about
bladder and urethra. ► (After sitting), Stiffness of muscles of legs.
► (After
standing), Aching and stiffness in back. ► (Touch),
Twitching of muscles; spasms; violent convulsions. ►
(Walking), Uneasiness about bladder
and urethra; burning in urethra; aching and stiffness in back; aching in
shin bones; aching in feet.
SUPPLEMENT: STRYCHNINUM.
Authorities.
162,
R. Gilsan, Amer. Journ. of Med. Sci., New Ser., No. 150, 1878, p. 449, a
man, æt. twenty-five years, took a dose; 163,
V. R. Bridges, M.D., Chicago Med. Journ. and Exam., 1879, p. 48, a girl,
æt. nine years, took an unknown quantity.►
I found him in terrible tetanic
convulsions. His legs and arms were extended, hands clenched, feet and
toes incurvated, and his body was rigidly arched backward, and resting
on his heels and back of his head. In short, all his muscles seemed to
be in a state of rigidity. There were also the risus
sardonicus, and a general cyanosed appearance of the skin.
During the paroxysm the pulse was too frequent to be counted, and his
pupils were slightly dilated. It was impossible on account of trismus
and the violence of the general spasms, to administer an emetic by the
mouth or to use the stomach-pump. The next morning I found him well, but
still feeling some muscular soreness and fatigue, and fully resolved to
let Strychnia alone in the future. He said no one could imagine the
fearful agony it had caused him, and that he would rather be burnt to
death than again suffer the pangs that he had endured from this horrible
poison. He told me also that after taking the Strychnia he locked the
door of his room, and lay down on his bed to die, as he supposed, in a
rapid and easy manner. When the spasms commenced they soon put him in
such fearful agony that he screamed for help, [162]. ►
Continuous and persistent spasm from head to foot, with an alarming and
distressing opisthotonos, rendered all the more painful from the fact
that she was entirely unconscious of her sufferings, while any effort to
relieve her by the slightest touch, or causing her to swallow, only
aggravated her condition, by apparently exciting every muscle to
increase its tension, [163].® 2000
Article